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Sickening: How Big Pharma Broke American…
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Sickening: How Big Pharma Broke American Health Care and How We Can Repair It (udgave 2022)

af John Abramson (Forfatter)

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371669,724 (4.21)1
The inside story of how Big Pharma's relentless pursuit of ever-higher profits corrupts medical knowledge - misleading doctors, misdirecting American health care, and harming our health. The United States spends an excess $1.5 trillion annually on health care compared to other wealthy countries - yet the amount of time that Americans live in good health ranks a lowly 68th in the world. At the heart of the problem is Big Pharma, which funds most clinical trials and therefore controls the research agenda, withholds the real data from those trials as corporate secrets, and shapes most of the information relied upon by health care professionals. In this no-holds-barred exposé, Dr. John Abramson - one of the foremost experts on the drug industry's deceptive tactics - combines patient stories with what he learned during many years of serving as an expert in national drug litigation to reveal the tangled web of financial interests at the heart of the dysfunction in our health-care system. For example, one of pharma's best-kept secrets is that the peer reviewers charged with ensuring the accuracy and completeness of the clinical trial reports published in medical journals do not even have access to complete data and must rely on manufacturer-influenced summaries. Likewise for the experts who write the clinical practice guidelines that define our standards of care. The result of years of research and privileged access to the inner workings of the U.S. medical-industrial complex, Sickening shines a light on the dark underbelly of American health care - and presents a path toward genuine reform.… (mere)
Medlem:CMDoherty
Titel:Sickening: How Big Pharma Broke American Health Care and How We Can Repair It
Forfattere:John Abramson (Forfatter)
Info:Mariner Books (2022), Edition: 1, 336 pages
Samlinger:Læser for øjeblikket, Læst, men ikke ejet
Vurdering:
Nøgleord:to-read

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Sickening: How Big Pharma Broke American Health Care and How We Can Repair It af John Abramson

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The premise of this book is that the US health care system is getting worse, and a large cause of this is big pharma. The US currrently spends nearly 20% of its GDP on health care, much, much more than any other wealth country, yet ranks 68th in quality of health care in the world. Over the last 40 years, funding for research and federal support of university-based research has declined, and the big drug companies have stepped in to fill the gap. Today, drug companies (big pharma) and commercial interests predominate in providing the information doctors rely on to determine patient treatment. Unfortunately, the primary goal of the drug companies is not to improve patient health, but to maximize profits. And unlike other countries, the US has allowed drug companies to charge as much as they want. (Note: Biden signed the bill today that allows Medicare to negotiate for at least some drug prices.)

The first part of the book goes through several examples of how drug companies have misled medical professionals to the detriment of patients. These included the Vioxx fiasco, which during the 5 years it was on the market was responsible for 88,000-140,000 heart attacks; Gabapentin, which is used off-label for neuropathic pain, and which is the 6th most prescribed drug in the US, but for which there is extremely limited evidence of effectiveness (beyond the placebo effect); Insulin- which has become more prescribed with changing definitions of A1C control, as well as changes the drug companies have made to insulin to make it more expensive, all without leading to better health outcomes; and, Statins--Prescribed for almost everyone of a certain age, despite limited evidence of benefits to women and healthy people at low risk for heart disease.

The second part of the book discusses how changes in Society from 1980 on have allowed commercial interests to control the medical knowledge that guides health care.

The third part discusses recent reforms including Obamacare.

Overall, an interesting look at healthcare.

3 stars ( )
  arubabookwoman | Sep 17, 2022 |
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The inside story of how Big Pharma's relentless pursuit of ever-higher profits corrupts medical knowledge - misleading doctors, misdirecting American health care, and harming our health. The United States spends an excess $1.5 trillion annually on health care compared to other wealthy countries - yet the amount of time that Americans live in good health ranks a lowly 68th in the world. At the heart of the problem is Big Pharma, which funds most clinical trials and therefore controls the research agenda, withholds the real data from those trials as corporate secrets, and shapes most of the information relied upon by health care professionals. In this no-holds-barred exposé, Dr. John Abramson - one of the foremost experts on the drug industry's deceptive tactics - combines patient stories with what he learned during many years of serving as an expert in national drug litigation to reveal the tangled web of financial interests at the heart of the dysfunction in our health-care system. For example, one of pharma's best-kept secrets is that the peer reviewers charged with ensuring the accuracy and completeness of the clinical trial reports published in medical journals do not even have access to complete data and must rely on manufacturer-influenced summaries. Likewise for the experts who write the clinical practice guidelines that define our standards of care. The result of years of research and privileged access to the inner workings of the U.S. medical-industrial complex, Sickening shines a light on the dark underbelly of American health care - and presents a path toward genuine reform.

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