Best friends Jack and Dave get an unwelcome surprise at the local Thanksgiving Turkey Trot race when they meet Kim, an attractive runner who strongly resembles Sylvie, a mysterious woman from Jack's past. To the complete dismay of Max, Jack's girlfriend, the surprise intensifies when the real Sylvie contacts Jack just hours later. Having returned to New England after a long rest in Florida, Sylvie claims that Kim is a hired killer who is armed, dangerous, and has a contract to kill her. Sylvie asks for Jack's help, and despite his better judgment and Max's initial protests, he still feels compelled to give it. When the chase between Kim and Sylvie heats up over the next set of frigid races, Jack and his friends get pulled deeper into their deadly game of cat and mouse, which can end with only one survivor.