The New Edition of this popular text features world-renowned experts who offer the most current information and reliable guidance on immunohistochemical diagnoses in surgical pathology and cytopathology. The book is organized in a consistent format of organ systems, specifically designed to target diagnostic dilemmas in surgical pathology. Each chapter features an introduction and a systematic approach to the diagnostic entities of that organ system. Readers will also find easy-to-understand diagnostic algorithms and "immunohistograms" that depict immunostaining patterns of tumors, as well as charts, tables, and high-quality color histologic images that assist in making a definitive diagnosis. Consistently organized chapters offer an introduction to the subject · a discussion of the biology of the relevant antigens and antibodies · a literature review · and numerous diagnostic algorithms and immunohistograms. Provides all the information readers need on a specific topic and eliminates the need to reference multiple areas of the text. Includes quick- reference boxes at the end of each section that summarize the most important diagnostic points. Provides separate method sections for diagnostic surgical pathology and immunocytology supply reference materials for the performance of diagnostic immunohistochemical tests. Features color photographs and illustrations that highlight key diagnostic points. Features updated and expanded antibody tables as well as the newest data on existing antibodies. Incorporates more hematopoietic markers. Presents key diagnostic points in each section that highlight the most pertinent aspects of that section and serve as a quick reference. Discusses potential diagnostic pitfalls and offers immunohistologic differential diagnosis where relevant. With 32 additional contributors.