I originally wanted this book because my sister has MS and I wanted to look for any hope of a cure. But once I received the book I realized that it was very medically technical and I didn't even attempt to read it.

I looked through this book briefly before sharing it with a family member who has MS. I am thankful for those who work to better understand and treat this disease.

I was interested in this book because I do have MS and wanted to see another point of view. There is no known cure or reasoning why a person get's this horrible disease. From what i read from the book it could be a possibility that the occlusion of your carotid artery could be a cause but is not yet proven. Not everyone that they have tested has this problem that they speak of in the book. I liked the book was not too hard to a laymen to read but i do have a lot of medical training. It has given me some good insite and questions for my Dr. ( )

This book is a key piece in understanding the complexity of a horrible and debilitating disease. It is a must-read for all who care for MS patients. Rhodes has prepared a very interesting book for the medical profession. By challenging the paradigm she stretches the reader's limits with readable factual data.

What I found exciting about this book is the clarity of thought, the focus, the well-referenced arguments, and the controversial topic. What Rhodes does is present a thesis that rather than being a disease of immune dysregulation, that MS is primarily a vascular disease. The resulting damage of specific damage in the the cerebro-spinal system is the cause of the disease we call multiple sclerosis.

While I personally do not believe that Rhodes thesis is correct, (I am personally a proponent of genetics as the etiology) she leave this as an open question. The vascular component of MS is clearly in need of greater research. Interestingly, the August 2011 issue of Nature discusses a multi-institutional study identifying 29 new genetic variants associated with MS with five being strongly linked to the disease. Rather than continuing a chicken-and egg discussion, this new research may lead to answers as to why there is abnormal angiogenesis in MS patients - ultimately leading to cures.

Rhodes book needs to be read by this group as they conduct further studies. Perhaps the answer is in some abnormal coding for angiogenisis on the genome. ( )

Thanks, to the LTER program and McFarland & Co. Inc. for my early reviewer copy. The author outlines developing theories about the possible cause for MS (multiple sclerosis). I have no medical training, yet found the book accessible and informative. A bit specious with regard to its conclusions, CCSVI as the Cause of Multiple Sclerosis is still a valuable resource when read in combination with other medical articles, books and literature, to produce a global view of the nature of MS.